Spontaneous post-implantation embryo resolution: A new concept in embryo loss

R. H. Asch, J. R. Verez, B. Asch, G. Najar, M. Cantarelli, G. B. La Sala, M. E. Vazquez, J. Stern, E. Macedo, R. Montanari, B. Valli

Research output: Contribution to journalArticlepeer-review


Objective: To determine and compare in an ART population the chances of complete abortion rate, and of spontaneous post-implantation embryo resolution (SPIER) (partial re-absorption of 1 or more gestational sacs) in clinical pregnancies according to the original number of gestational sacs observed. Design: A prospective, on going study in a University-based private practice and in a public hospital facility ART units. Materials and Methods: We studied the outcome of 620 pregnancies originated from ART. There were 414 singletons (67%), 132 twins (21%), 48 triplets (8%), 19 quadruplets (3%) and 7 quintuplets (1%). At the first ultrasound observation of the clinical pregnancies (20-30 days, post-conception) we detected 414 single gestational scans (44%), 264 double (28%), 144 triple (10%) 76 quadruple (8%) and 35 quintuple sacs (4%). Results: A) complete pregnancy loss was observed in 22% of all pregnancies (n:160) with the following distribution: Singleton (29%), twin (10%), triplet (8%), quadruplet pregnancies (10%), and quintuplets (14%) respectively. The pregnancy loss decreased proportional to the magnitude of the multiple gestation, being statistically significantly higher in the group of patients with singletons (p

Original languageEnglish
Pages (from-to)43-46
Number of pages4
JournalMiddle East Fertility Society Journal
Issue number1
Publication statusPublished - 1998


  • Abortion rate
  • Embryo resolution

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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