TY - JOUR
T1 - Spontaneous regression of optic pathways gliomas in three patients with neurofibromatosis type I and critical review of the literature
AU - Piccirilli, Manolo
AU - Lenzi, Jacopo
AU - Delfinis, Catia
AU - Trasimeni, Guido
AU - Salvati, Maurizio
AU - Raco, Antonino
PY - 2006/10
Y1 - 2006/10
N2 - Case reports: The authors report their experience about three children (two girls, one boy; average age 1.6 years) with a spontaneous regression of optic gliomas. All of them had a previous diagnosis of neurofibromatosis type 1 (NF 1). None of them underwent surgery or biopsy nor received chemotherapy or radiotherapy. The complete regression was documented by MRI scans performed during a mean follow-up of 6.3 years. Literature review: Moreover, the authors analyze the features of the 16 cases previously reported in English literature of spontaneously regressed optic gliomas with an overview of the different therapeutic strategies. The knowledge that this kind of tumor, particularly in young patients, may regress is important in the decision of the best therapeutic approach.
AB - Case reports: The authors report their experience about three children (two girls, one boy; average age 1.6 years) with a spontaneous regression of optic gliomas. All of them had a previous diagnosis of neurofibromatosis type 1 (NF 1). None of them underwent surgery or biopsy nor received chemotherapy or radiotherapy. The complete regression was documented by MRI scans performed during a mean follow-up of 6.3 years. Literature review: Moreover, the authors analyze the features of the 16 cases previously reported in English literature of spontaneously regressed optic gliomas with an overview of the different therapeutic strategies. The knowledge that this kind of tumor, particularly in young patients, may regress is important in the decision of the best therapeutic approach.
KW - Magnetic resonance imaging
KW - Neurofibromatosis type I
KW - Optic gliomas
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U2 - 10.1007/s00381-006-0061-3
DO - 10.1007/s00381-006-0061-3
M3 - Article
C2 - 16639629
AN - SCOPUS:33747765029
VL - 22
SP - 1332
EP - 1337
JO - Child's Nervous System
JF - Child's Nervous System
SN - 0256-7040
IS - 10
ER -