Spontaneous retinal pigment epithelium tear in geographic atrophy

E. Cavallero, F. Corvi, E. Souied, F. Bandello, G. Querques

Research output: Contribution to journalArticlepeer-review


Purpose: To report two cases of spontaneous retinal pigment epithelial (RPE) tears occurring in two patients affected with geographic atrophy (GA) due to non-exudative age-related macular degeneration (AMD). Case report: Two patients (a 79-year-old man and a 71-year-old woman) presented to our department with progressive visual loss. The man had a best-corrected visual acuity (BCVA) of 20/100 in the right eye (RE) and 20/50 in the left eye (LE); the woman had a BCVA of 20/200 in the RE and 20/160 in the LE. Upon complete ophthalmologic examination, revealing a large area of atrophy (>. 175. μm in diameter) along with pigmentary changes, calcified drusen and no choroidal neovascularization (CNV) in either eye, the patients were diagnosed with GA due to non-exudative AMD. Interestingly, the imaging modalities performed, including fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral-domain optical coherence tomography (SD-OCT), clearly highlighted the presence of spontaneous RPE tears in the context of non-exudative AMD, while in general, RPE tears are a well-recognized complication of exudative AMD. Conclusions: To our knowledge, this is the first description of spontaneous RPE tears as a possible complication of GA due to non-exudative AMD.

Original languageEnglish
JournalJournal Francais d'Ophtalmologie
Publication statusAccepted/In press - Mar 12 2015


  • Age-related macular degeneration
  • Geographic atrophy
  • Pigment epithelial detachment
  • Retinal pigment epithelium
  • Tear

ASJC Scopus subject areas

  • Ophthalmology

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