Sporadic endolymphatic sac tumor: Its clinical, radiological, and histological features, management, and follow-up

Arturo M. Poletti, Siba P. Dubey, Regina Barbò, Sergio Pericotti, Barbara Fiamengo, Giovanni Colombo, Marta Scorsetti, Rosaria Lorusso, Antonio Mazzoni

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background Sporadic endolymphatic sac tumor (ELST) is rare. We described the clinical, radiological, and histological features, treatment, and follow-up of ELST. Method This was a retrospective analysis of 7 cases of sporadic ELST that were managed between 1993 and 2010. Results Twenty-five to 75 years was the age range of the patients. Subjective hearing loss and tinnitus were the most common presenting features. Five patients had total deafness and 2 had severe sensorineural hearing loss. The most common radiological feature was temporal bone destruction with tumor extension to cerebellopontine angle and posterior cranial fossa. Cholesterol or hemosiderin cysts around the tumor could be a characteristic feature. Major skull base procedures were performed in all 7 cases, and complete tumor excision was achieved in 6 of them. One patient needed a second surgery after she was referred to us after an incomplete first surgery. Recurrences were detected in 2 patients during follow-up; 1 of them received irradiation without minimal change to the tumor size and the second refused any treatment for the recurrence. Both of them are alive with disease. Conclusion Early detection and radical surgical excision at first attempt give best results. Radiotherapy could be considered only in unresectable recurrences.

Original languageEnglish
Pages (from-to)1043-1047
Number of pages5
JournalHead and Neck
Volume35
Issue number7
DOIs
Publication statusPublished - Jul 2013

Fingerprint

Endolymphatic Sac
Neoplasms
Recurrence
Hemosiderin
Cerebellopontine Angle
Posterior Cranial Fossa
Tinnitus
Sensorineural Hearing Loss
Temporal Bone
Skull Base
Deafness
Hearing Loss
Cysts
Radiotherapy
Cholesterol
Therapeutics

Keywords

  • cerebellopontine angle
  • endolymphatic sac
  • low grade adenocarcinoma
  • temporal bone
  • tumor

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Poletti, A. M., Dubey, S. P., Barbò, R., Pericotti, S., Fiamengo, B., Colombo, G., ... Mazzoni, A. (2013). Sporadic endolymphatic sac tumor: Its clinical, radiological, and histological features, management, and follow-up. Head and Neck, 35(7), 1043-1047. https://doi.org/10.1002/hed.22962

Sporadic endolymphatic sac tumor : Its clinical, radiological, and histological features, management, and follow-up. / Poletti, Arturo M.; Dubey, Siba P.; Barbò, Regina; Pericotti, Sergio; Fiamengo, Barbara; Colombo, Giovanni; Scorsetti, Marta; Lorusso, Rosaria; Mazzoni, Antonio.

In: Head and Neck, Vol. 35, No. 7, 07.2013, p. 1043-1047.

Research output: Contribution to journalArticle

Poletti, AM, Dubey, SP, Barbò, R, Pericotti, S, Fiamengo, B, Colombo, G, Scorsetti, M, Lorusso, R & Mazzoni, A 2013, 'Sporadic endolymphatic sac tumor: Its clinical, radiological, and histological features, management, and follow-up', Head and Neck, vol. 35, no. 7, pp. 1043-1047. https://doi.org/10.1002/hed.22962
Poletti, Arturo M. ; Dubey, Siba P. ; Barbò, Regina ; Pericotti, Sergio ; Fiamengo, Barbara ; Colombo, Giovanni ; Scorsetti, Marta ; Lorusso, Rosaria ; Mazzoni, Antonio. / Sporadic endolymphatic sac tumor : Its clinical, radiological, and histological features, management, and follow-up. In: Head and Neck. 2013 ; Vol. 35, No. 7. pp. 1043-1047.
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