Squalene chemistry and biology

Emanuela Camera; Monica Ottaviani; Mauro Picardo

doi:10.1007/978-3-319-09943-9_12

Squalene chemistry and biology

Emanuela Camera, Monica Ottaviani, Mauro Picardo

Istituto S. Maria e S. Gallicano

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Human sebum is renowned as a unique mixture of lipids. Although the complexity of human sebum composition is suggestive of the multiplicity of sebum functions, squalene deserves a special focus due to its extraordinary abundance on human skin. Noteworthy, squalene is the main standalone and unsaponifiable component in sebum. The majority of sebaceous lipid components are members of lipid families, such as fatty acids (FA), triglycerides (TG), wax esters (WE), and cholesterol esters (CE). In particular, TG together with free FA account for the 40–60 % of the sebum weight, followed by WE (19–26 %), and squalene (10–15 %). Although minimal amounts of cholesterol are measurable in sebum, its exact origin is still unclear.

Original language	English
Title of host publication	Lipids and Skin Health
Publisher	Springer International Publishing
Pages	185-198
Number of pages	14
ISBN (Print)	9783319099439, 9783319099422
DOIs	https://doi.org/10.1007/978-3-319-09943-9_12
Publication status	Published - Jan 1 2015

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)
Engineering(all)
Agricultural and Biological Sciences(all)

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