TY - JOUR
T1 - Squamous cell carcinoma antigen (SCC-Ag) during follow-up of cervical cancer patients
T2 - Role in the early diagnosis of recurrence
AU - Salvatici, Michela
AU - Achilarre, Maria T.
AU - Sandri, Maria T.
AU - Boveri, Sara
AU - Vanna, Zanagnolo
AU - Landoni, Fabio
PY - 2015/12/18
Y1 - 2015/12/18
N2 - Objective: The aim of this study was to assess the potential benefit of routine squamous cell carcinoma antigen (SCC-Ag) assessment during follow-up of patients after treatment for early cervical cancer with regard to early diagnosis of cancer recurrence before clinical signs and symptoms occur. Methods: All clinical, pathological, and serological data of patients referred to the Department of Gynecologic Oncology between July 1999 and June 2014, were retrospectively collected and analyzed. The SCC-Ag levels of 197 patients with diagnosis of stage I or II cervical squamous carcinoma, were performed. Results: In the univariate analysis, serum SCC-Ag was not significantly associated with grading (p = 0.85), LVSI (p = 0.95) and FIGO stage (p = 0.83) but it was significantly associated with recurrence of disease (p
AB - Objective: The aim of this study was to assess the potential benefit of routine squamous cell carcinoma antigen (SCC-Ag) assessment during follow-up of patients after treatment for early cervical cancer with regard to early diagnosis of cancer recurrence before clinical signs and symptoms occur. Methods: All clinical, pathological, and serological data of patients referred to the Department of Gynecologic Oncology between July 1999 and June 2014, were retrospectively collected and analyzed. The SCC-Ag levels of 197 patients with diagnosis of stage I or II cervical squamous carcinoma, were performed. Results: In the univariate analysis, serum SCC-Ag was not significantly associated with grading (p = 0.85), LVSI (p = 0.95) and FIGO stage (p = 0.83) but it was significantly associated with recurrence of disease (p
KW - Cervical cancer
KW - Early detection
KW - Recurrence
KW - Squamous cell carcinoma antigen
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U2 - 10.1016/j.ygyno.2016.04.029
DO - 10.1016/j.ygyno.2016.04.029
M3 - Article
AN - SCOPUS:84965047644
JO - Gynecologic Oncology
JF - Gynecologic Oncology
SN - 0090-8258
ER -