Squamous cell carcinoma antigen (SCC-Ag) during follow-up of cervical cancer patients: Role in the early diagnosis of recurrence

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Abstract

Objective: The aim of this study was to assess the potential benefit of routine squamous cell carcinoma antigen (SCC-Ag) assessment during follow-up of patients after treatment for early cervical cancer with regard to early diagnosis of cancer recurrence before clinical signs and symptoms occur. Methods: All clinical, pathological, and serological data of patients referred to the Department of Gynecologic Oncology between July 1999 and June 2014, were retrospectively collected and analyzed. The SCC-Ag levels of 197 patients with diagnosis of stage I or II cervical squamous carcinoma, were performed. Results: In the univariate analysis, serum SCC-Ag was not significantly associated with grading (p = 0.85), LVSI (p = 0.95) and FIGO stage (p = 0.83) but it was significantly associated with recurrence of disease (p

Original languageEnglish
JournalGynecologic Oncology
DOIs
Publication statusAccepted/In press - Dec 18 2015

Keywords

  • Cervical cancer
  • Early detection
  • Recurrence
  • Squamous cell carcinoma antigen

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

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