Stage 4 diffuse lamellar keratitis after laser in situ keratomileusis: Clinical, topographical, and pachymetry resolution 5 years later

Paolo Michieletto, Alessandra Balestrazzi, Angelo Balestrazzi, Marco Alegente, Barbara Boccassini

Research output: Contribution to journalArticle


In March 1999, a 35-year-old woman had uneventful laser in situ keratomileusis in both eyes on the same day. Five days postoperatively, slitlamp biomicroscopy of the left eye showed an appearance similar to haze after photorefractive keratectomy, with greater density at the center and striae convergent toward the infiltrate (stage 4 diffuse lamellar keratitis [DLK]). The patient received treatment with dexamethasone 0.2% eyedrops every 2 hours. After 2 weeks, visual acuity was better and improvement was evident on topography, pachymetry, and slitlamp photography. The improvements were more marked at 6 months and 1 year. There was a progressive increment in corneal thickness and consequent improvement in corneal transparency, curvature, and regularity. This case, in which continuous morphologic adaptation of the cornea occurred, indicates that observation, rather than intervention, is a valid therapeutic option for stage 4 DLK.

Original languageEnglish
Pages (from-to)353-356
Number of pages4
JournalJournal of Cataract and Refractive Surgery
Issue number2
Publication statusPublished - Feb 2006


ASJC Scopus subject areas

  • Ophthalmology

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