Stages of early acute renal dysfunction in liver transplantation: The influence of graft function

I. Umbro, M. Rossi, F. Tinti, F. Fiacco, P. Piselli, S. Ianni, S. Ginanni Corradini, L. Poli, P. B. Berloco, A. P. Mitterhofer

Research output: Contribution to journalArticlepeer-review

Abstract

The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.

Original languageEnglish
Pages (from-to)1953-1955
Number of pages3
JournalTransplantation Proceedings
Volume44
Issue number7
DOIs
Publication statusPublished - Sep 2012

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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