Standard versus eversion-modified double-staple technique for low colorectal anastomoses after resection of rectal cancer

Giulio Illuminati, Rocco Pasqua, Bruno Perotti, Paolo Urciuoli, Priscilla Nardi, Chiara Fratini, Fabio Carboni, Mario Valle

Research output: Contribution to journalArticlepeer-review


Purpose: The double-staple technique, performed as either the standard procedure or after eversion of the rectal stump, is a well-established method of performing low colorectal anastomoses following the resection of rectal cancer. Eversion of the tumor-bearing ano-rectal stump was proposed to allow the linear stapler to be fired at a safe distance of clearance from the tumor. We conducted this study to compare the results of the standard versus the eversion-modified double-staple technique. Methods: The subjects of this retrospective study were 753 consecutive patients who underwent low stapled colorectal anastomosis after resection of rectal cancer. The patients were divided into two groups according to the method of anastomosis used: Group A comprised 165 patients (22%) treated with the modified eversion technique and group B comprised 588 patients (78%) treated with the standard technique. The primary endpoints of the study were postoperative mortality, surgery-related morbidity, the number of sampled lymph nodes in the mesorectum, and late disease-related survival. Results: Postoperative mortality was 1.2% in group A and 1.7% in group B (p = 0.66). Postoperative morbidity was 12% in group A and 11% in group B (p = 0.75). The mean number of sampled lymph nodes in the mesorectum was 23 (range 17–27) in group A and 24 (range 19–29) in group B (p = 0.06). The 5-year disease-related survival was 73% in group A and 74% in group B (p = 0.75). Conclusion: The standard and eversion-modified double-staple techniques yield comparable results.

Original languageEnglish
JournalSurgery Today
Publication statusAccepted/In press - 2020


  • Colorectal cancer
  • Double-stapled colorectal anastomosis
  • Stapling technique

ASJC Scopus subject areas

  • Surgery


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