Standardization procedure for flow cytometry data harmonization in prospective multicenter studies

PRECISESADS Flow Cytometry Study Group, PRECISESADS Clinical Consortium

Research output: Contribution to journalArticlepeer-review

Abstract

One of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projects.

Original languageEnglish
Article number11567
JournalScientific Reports
Volume10
Issue number1
DOIs
Publication statusPublished - Dec 1 2020

ASJC Scopus subject areas

  • General

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