Standardized remission criteria in schizophrenia

J. Van Os, T. Burns, R. Cavallaro, S. Leucht, J. Peuskens, L. Helldin, M. Bernardo, C. Arango, W. Fleischhacker, B. Lachaux, J. M. Kane

Research output: Contribution to journalArticle

187 Citations (Scopus)

Abstract

Objective: Recent work has focussed on schizophrenia as a 'deficit' state but little attention has been paid to defining illness plasticity in terms of symptomatic remission. Method: A qualitative review of a recently proposed concept of remission [N.C. Andreasen, W.T. Carpenter Jr, J.M. Kane, R.A. Lasser, S.R. Marder, D.R. Weinberger (2005) Am J Psychiatry 162: 441] is presented. Results: The proposed definition of remission is conceptually viable, and can be easily implemented in clinical trials and clinical practice. Its increasing acceptance may reset expectations of treatment to a higher level, improve documentation of clinical status and facilitate dialogue on treatment expectations. The availability of validated outcome measures based on remission will enhance the conduct and reporting of clinical investigations, and could facilitate the design and interpretation of new studies on cognition and functional outcomes. While useful as a concept, it is important to consider that remission is distinct from recovery. Conclusion: The introduction of standardized remission criteria may offer significant opportunities for clinical practice, health services research and clinical trials.

Original languageEnglish
Pages (from-to)91-95
Number of pages5
JournalActa Psychiatrica Scandinavica
Volume113
Issue number2
DOIs
Publication statusPublished - Feb 2006

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Schizophrenia
Clinical Trials
Health Services Research
Documentation
Cognition
Psychiatry
Outcome Assessment (Health Care)

Keywords

  • Prognosis
  • Psychotic disorders
  • Schizophrenia
  • Therapeutics
  • Treatment outcome

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Van Os, J., Burns, T., Cavallaro, R., Leucht, S., Peuskens, J., Helldin, L., ... Kane, J. M. (2006). Standardized remission criteria in schizophrenia. Acta Psychiatrica Scandinavica, 113(2), 91-95. https://doi.org/10.1111/j.1600-0447.2005.00659.x

Standardized remission criteria in schizophrenia. / Van Os, J.; Burns, T.; Cavallaro, R.; Leucht, S.; Peuskens, J.; Helldin, L.; Bernardo, M.; Arango, C.; Fleischhacker, W.; Lachaux, B.; Kane, J. M.

In: Acta Psychiatrica Scandinavica, Vol. 113, No. 2, 02.2006, p. 91-95.

Research output: Contribution to journalArticle

Van Os, J, Burns, T, Cavallaro, R, Leucht, S, Peuskens, J, Helldin, L, Bernardo, M, Arango, C, Fleischhacker, W, Lachaux, B & Kane, JM 2006, 'Standardized remission criteria in schizophrenia', Acta Psychiatrica Scandinavica, vol. 113, no. 2, pp. 91-95. https://doi.org/10.1111/j.1600-0447.2005.00659.x
Van Os, J. ; Burns, T. ; Cavallaro, R. ; Leucht, S. ; Peuskens, J. ; Helldin, L. ; Bernardo, M. ; Arango, C. ; Fleischhacker, W. ; Lachaux, B. ; Kane, J. M. / Standardized remission criteria in schizophrenia. In: Acta Psychiatrica Scandinavica. 2006 ; Vol. 113, No. 2. pp. 91-95.
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