Staphylococcus aureus bacteremia in patients with hematologic malignancies: A retrospective case-control study

Mario Venditri, Marco Falcone, Alessandra Micozzi, Paolo Carfagna, Fabrizio Taglietti, Pietro F. Serra, Pietro Martino

Research output: Contribution to journalArticle

Abstract

Background and Objectives. Staphylococcus aureus bacteremia (SAB) continues to be a major problem related to both community and nosocomially acquired infection. Nevertheless few data are presently available in literature about this infection in patients with hematologic malignancies. Design and Methods. The purpose of this retrospective study was to report further data on the clinical characteristics and outcome of patients with SAB. All episodes of SAB occurring between January 1997 and June 2001 were identified and defined by analysis of the patients' clinical records. Results. The nosocomial mortality rate was only 3.5% and no patient developed secondary complications. Comparison between neutropenic hematologic patients with SAB and neutropenic hematologic patients with Gram-negative bacteremia (GNB) revealed an higher mortality in the latter group (p=0.03); furthermore, severe sepsis and septic shock were more frequent in patients with GNB (p

Original languageEnglish
Pages (from-to)923-930
Number of pages8
JournalHaematologica
Volume88
Issue number8
Publication statusPublished - Aug 1 2003

Keywords

  • Hematologic malignancies
  • Inflammatory response
  • Staphylococcus aureus bacteremia

ASJC Scopus subject areas

  • Hematology

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    Venditri, M., Falcone, M., Micozzi, A., Carfagna, P., Taglietti, F., Serra, P. F., & Martino, P. (2003). Staphylococcus aureus bacteremia in patients with hematologic malignancies: A retrospective case-control study. Haematologica, 88(8), 923-930.