The response to StaCW and SPA of highly purified populations of peripheral blood and tonsil human lymphocytes was investigated. Purified T lymphocytes from peripheral blood were unable to respond in vitro to StaCw, whereas highly purified B lymphocytes from peripheral blood and tonsil were able to respond to StaCw, even in the absence of T lymphocytes. Highly purified B lymphocytes from tonsil did not show any proliferative response in the presence of soluble SPA, whereas they responded well to SPA coupled to Sepharose beads. The response of B lymphocytes to soluble SPA was dependent on the presence of T lymphocytes.
|Translated title of the contribution||Staphylococcus aureus Cowan I: A T-cell independent B-cell mitogen|
|Number of pages||4|
|Journal||Folia Allergologica et Immunologica Clinica|
|Publication status||Published - 1978|
ASJC Scopus subject areas
- Immunology and Allergy