State-of-the-art approach for bone sarcomas

Andreas F. Mavrogenis, Andrea Angelini, Christos Vottis, Emanuela Palmerini, Eugenio Rimondi, Giuseppe Rossi, Panayiotis J. Papagelopoulos, Pietro Ruggieri

Research output: Contribution to journalArticlepeer-review


Bone sarcomas are a variety of non-epithelial, malignant neoplasms of bone. The most common bone sarcomas are osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. The approach to a patient with a suspected bone sarcoma from initial examination to the histological diagnosis and classification is staging. Staging is of critical importance, in order to classify different treatment options and point out which combination of them is more suitable depending on the severity of the tumor in every individual patient. Staging should include medical history, physical and imaging examination, and biopsy. This article presents the current approach for staging, principles of biopsy, tumor classification, treatment, and follow-up of patients with bone sarcomas.

Original languageEnglish
Pages (from-to)5-15
Number of pages11
JournalEuropean Journal of Orthopaedic Surgery and Traumatology
Issue number1
Publication statusPublished - May 3 2014


  • Biopsy
  • Bone sarcoma
  • Chemotherapy
  • Radiation therapy
  • Staging
  • Surgery

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine
  • Medicine(all)


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