Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals

Anna Maria Brambilla, Roberto Novati, Giliola Calori, Elena Meneghini, Daniela Vacchini, Livio Luzi, Antonella Castagna, Adriano Lazzarin

Research output: Contribution to journalArticlepeer-review

Abstract

Diabetes mellitus was diagnosed in 16 out of 1011 HIV-positive patients over a median follow-up of 289 days (person-year incidence 2.06, 95% confidence interval 1.18-3.33). Significant risk factors for the onset of diabetes were older age and antiretroviral therapy with stavudine or indinavir. Older men with HIV infection should be considered at higher risk of diabetes, and caution may be warranted in the use of both indinavir and stavudine in these patients.

Original languageEnglish
Pages (from-to)1993-1995
Number of pages3
JournalAIDS (London, England)
Volume17
Issue number13
DOIs
Publication statusPublished - Sep 5 2003

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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