Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals

Anna Maria Brambilla; Roberto Novati; Giliola Calori; Elena Meneghini; Daniela Vacchini; Livio Luzi; Antonella Castagna; Adriano Lazzarin

doi:10.1097/00002030-200309050-00022

Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals

Anna Maria Brambilla, Roberto Novati, Giliola Calori, Elena Meneghini, Daniela Vacchini, Livio Luzi, Antonella Castagna, Adriano Lazzarin

Research output: Contribution to journal › Article › peer-review

Abstract

Diabetes mellitus was diagnosed in 16 out of 1011 HIV-positive patients over a median follow-up of 289 days (person-year incidence 2.06, 95% confidence interval 1.18-3.33). Significant risk factors for the onset of diabetes were older age and antiretroviral therapy with stavudine or indinavir. Older men with HIV infection should be considered at higher risk of diabetes, and caution may be warranted in the use of both indinavir and stavudine in these patients.

Original language	English
Pages (from-to)	1993-1995
Number of pages	3
Journal	AIDS (London, England)
Volume	17
Issue number	13
DOIs	https://doi.org/10.1097/00002030-200309050-00022
Publication status	Published - Sep 5 2003

ASJC Scopus subject areas

Immunology
Immunology and Allergy

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Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals. / Brambilla, Anna Maria; Novati, Roberto; Calori, Giliola; Meneghini, Elena; Vacchini, Daniela; Luzi, Livio ; Castagna, Antonella; Lazzarin, Adriano.

In: AIDS (London, England), Vol. 17, No. 13, 05.09.2003, p. 1993-1995.

Research output: Contribution to journal › Article › peer-review

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title = "Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals",

abstract = "Diabetes mellitus was diagnosed in 16 out of 1011 HIV-positive patients over a median follow-up of 289 days (person-year incidence 2.06, 95% confidence interval 1.18-3.33). Significant risk factors for the onset of diabetes were older age and antiretroviral therapy with stavudine or indinavir. Older men with HIV infection should be considered at higher risk of diabetes, and caution may be warranted in the use of both indinavir and stavudine in these patients.",

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AU - Brambilla, Anna Maria

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AU - Calori, Giliola

AU - Meneghini, Elena

AU - Vacchini, Daniela

AU - Luzi, Livio

AU - Castagna, Antonella

AU - Lazzarin, Adriano

PY - 2003/9/5

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N2 - Diabetes mellitus was diagnosed in 16 out of 1011 HIV-positive patients over a median follow-up of 289 days (person-year incidence 2.06, 95% confidence interval 1.18-3.33). Significant risk factors for the onset of diabetes were older age and antiretroviral therapy with stavudine or indinavir. Older men with HIV infection should be considered at higher risk of diabetes, and caution may be warranted in the use of both indinavir and stavudine in these patients.

AB - Diabetes mellitus was diagnosed in 16 out of 1011 HIV-positive patients over a median follow-up of 289 days (person-year incidence 2.06, 95% confidence interval 1.18-3.33). Significant risk factors for the onset of diabetes were older age and antiretroviral therapy with stavudine or indinavir. Older men with HIV infection should be considered at higher risk of diabetes, and caution may be warranted in the use of both indinavir and stavudine in these patients.

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Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals

Abstract

ASJC Scopus subject areas

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