Stem cells: From animal research to clinical applications

C. Redi, M. Monti, V. Merico, T. Neri, M. Zanoni, M. Zuccotti, S. Garagna

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The application of stem cells to regenerative medicine is one of the actual hot topics in biomedicine. This research could help the cure of a number of diseases that are affecting a large share of the population. Some good results in cell replacement have already been obtained (infarcted heart, diabetes, Parkinson disease), apart from those of more traditional applications like severe burns and blood tumors. We are now facing crucial questions in stem cell biology. One of the key questions is how a cell begins to proliferate or differentiate. Genome reprogramming, both following nuclear transfer and cytoplast action, will likely highlight some of the molecular mechanisms of cell differentiation and dedifferentiation. In turn, these clues should be useful to the production of populations of reprogrammed cells that could develop into tissues or, in the future, into proper organs. We will overview what stem cells are, what roles they play in normal developmental processes and how stem cells could have the potential to treat diseases.

Original languageEnglish
Title of host publicationEndocrine Development
Pages145-151
Number of pages7
Volume11
DOIs
Publication statusPublished - 2007

Publication series

NameEndocrine Development
Volume11
ISSN (Print)14217082
ISSN (Electronic)16622979

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Pediatrics, Perinatology, and Child Health
  • Endocrinology
  • Endocrine and Autonomic Systems
  • Medicine(all)

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  • Cite this

    Redi, C., Monti, M., Merico, V., Neri, T., Zanoni, M., Zuccotti, M., & Garagna, S. (2007). Stem cells: From animal research to clinical applications. In Endocrine Development (Vol. 11, pp. 145-151). (Endocrine Development; Vol. 11). https://doi.org/10.1159/000111070