Stenting of aortic coarctation and exercise-induced hypertension in the young

Enrico De Caro, Isabella Spadoni, Roberto Crepaz, Michele Saitta, Gianluca Trocchio, M. G. Calevo, Giacomo Pongiglione

Research output: Contribution to journalArticle

Abstract

Objectives: To evaluate whether the stenting of aortic coarctation enhance the risk of exercise-induced hypertension (EIH). Background: There is the theoretical concern that aortic stents may cause increased aortic wall impedance and therefore systolic hypertension during exercise. Methods: Blood pressure and the Doppler derived peak and mean systolic pressure gradient (PSG and MSG) across the distal aorta at the peak of exercise were evaluated in young patients (mean age 14 ± 3 years)with aortic coarctation successfully treated with surgery or with stent implantation at least 1 year before the test. Only patients who reached the 85% maximal predicted heart rate or whose exercise test was interrupted because of severe hypertension, and in whom significant aortic narrowings were excluded by a MRI or a CT scan performed in the six months preceding the exercise test were included in the study. Results: Seventeen patients formed the surgery-group, while 15 patients the stent-group. Patients in surgery-group were younger at coarctation repair and with a longer follow-up than those in stentgroup. No difference was present regarding age, body surface area, gender, and presence, and degree of mildly hypoplastic aortic segments between the two groups as well as between patients with or without EIH. EIH was found in 35% of surgery-group patients and in 33% of stent-group patients. PSG and MSG were similar in the patients with or without EIH. Conclusions: EIH can be found in a high number of young patients successfully treated for aortic coarctation but at intermediate follow-up stent implantation does not seem to enhance the risk of EIH.

Original languageEnglish
Pages (from-to)256-261
Number of pages6
JournalCatheterization and Cardiovascular Interventions
Volume75
Issue number2
DOIs
Publication statusPublished - Feb 1 2010

Keywords

  • Congenital heart disease in adults
  • Hemodynamics
  • Imaging (CT/MR)
  • Pediatric interventions

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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