Stenting of culprit lesions in unstable angina leads to a marked reduction in plaque burden: A major role of plaque embolization? A serial intravascular ultrasound study

Francesco Prati, Tomasz Pawłowski, Robert Gil, Antonella Labellarte, Aneta Gziut, Eugenio Caradonna, Alessandro Manzoli, Alessandro Pappalardo, Francesco Burzotta, Alessandro Boccanelli

Research output: Contribution to journalArticlepeer-review

Abstract

Background - Intravascular ultrasound (IVUS) studies have shown that a mechanism of plaque compression/embolization contributes toward the poststenting increase in lumen area. The aim of this IVUS study was to compare the mechanisms of lumen enlargement after coronary stenting in 54 consecutive patients with unstable angina (UA) (group 1) and 56 with stable angina (group 2) to verify whether plaque embolization plays a major role in the former. Methods and Results - Both groups underwent the IVUS assessment (speed, 0.5 mm/sec) before the intervention and after stent implantation. The lumen area, the external elastic membrane area, and the plaque+media area (PA) were measured at 0.5-mm intervals. PA reduction in the lesion site was significantly greater in group 1 (-2.50+1.97 versus -0.53±1.43 mm2, P

Original languageEnglish
Pages (from-to)2320-2325
Number of pages6
JournalCirculation
Volume107
Issue number18
DOIs
Publication statusPublished - May 13 2003

Keywords

  • Angioplasty
  • Stents
  • Ultrasonics

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

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