Stereotactic biopsy approach to the upper clivus through the middle fossa floor that avoids pneumatised cavities and the intradural compartment

Lorenzo Magrassi, Elena Moretti, Marco Marchionni, Elisa Rognone, Bonfichi Maurizio

Research output: Contribution to journalArticle


BACKGROUND: Biopsies of clival lesions are usually performed, under general anaesthesia, through an anterior endoscopic approach or, alternatively, through a trans-nasal or trans-oral stereotactic approach.

METHODS: A 57-year-old man with a symptomatic osteolytical lesion of the clivus, who refused general anaesthesia, underwent a sterotactically guided biopsy of the lesion by an antero-lateral approach through the temporal and sphenoid bones.

RESULTS: Biopsy was successfully performed and the resulting diagnosis was myeloma. The patient was comfortable during and after surgery and there were no complications.

CONCLUSIONS: The present stereotactic antero-lateral approach to the biopsy of the upper clivus can be considered an useful adjunct to the current trans-oral and transnasal approaches that often require general anaesthesia.

Original languageEnglish
Pages (from-to)717-20
Number of pages4
JournalActa Neurochirurgica
Issue number4
Publication statusPublished - Apr 2016



  • Biopsy/methods
  • Dura Mater/surgery
  • Humans
  • Male
  • Middle Aged
  • Multiple Myeloma/pathology
  • Neuroendoscopy/methods
  • Neuronavigation/methods
  • Skull Base/surgery
  • Skull Neoplasms/pathology

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