Stereotactic management of craniopharyngiomas

Franco Frank, Antonio P. Fabrizi, Giorgio Frank, Antonio Fioravanti

Research output: Contribution to journalArticlepeer-review


The authors present a series of 47 patients with craniopharyngiomas treated by stereotaxy in the past 15 years. There was no mortality nor immediate postoperative morbidity in the treatment of the cystic portion of the neoplasm. Intracavitary colloidal yttrium (90Y) was extremely effective in obtaining long-lasting disappearance of craniopharyngioma cysts. In children, yttrium worsened panhypopituitarism, while it was well tolerated by teenagers and adults. Craniopharyngiomas are often mixed (solid-cystic) and the majority of cases have a predominant cystic portion, where stereotaxy is a valid alternative to open surgery, which presents a high morbidity and mortality.

Original languageEnglish
Pages (from-to)176-183
Number of pages8
JournalStereotactic and Functional Neurosurgery
Issue number1-4
Publication statusPublished - 1995


  • Craniopharyngiomas
  • Intracavitary yttrium
  • Intracystic bleomycin
  • Iodine-125
  • Yttrium-90

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery


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