Stereotactic management of craniopharyngiomas

Franco Frank; Antonio P. Fabrizi; Giorgio Frank; Antonio Fioravanti

doi:10.1159/000098691

Stereotactic management of craniopharyngiomas

Franco Frank, Antonio P. Fabrizi, Giorgio Frank, Antonio Fioravanti

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Abstract

The authors present a series of 47 patients with craniopharyngiomas treated by stereotaxy in the past 15 years. There was no mortality nor immediate postoperative morbidity in the treatment of the cystic portion of the neoplasm. Intracavitary colloidal yttrium (⁹⁰Y) was extremely effective in obtaining long-lasting disappearance of craniopharyngioma cysts. In children, yttrium worsened panhypopituitarism, while it was well tolerated by teenagers and adults. Craniopharyngiomas are often mixed (solid-cystic) and the majority of cases have a predominant cystic portion, where stereotaxy is a valid alternative to open surgery, which presents a high morbidity and mortality.

Original language	English
Pages (from-to)	176-183
Number of pages	8
Journal	Stereotactic and Functional Neurosurgery
Volume	65
Issue number	1-4
DOIs	https://doi.org/10.1159/000098691
Publication status	Published - 1995

Keywords

Craniopharyngiomas
Intracavitary yttrium
Intracystic bleomycin
Iodine-125
Yttrium-90

ASJC Scopus subject areas

Clinical Neurology
Surgery

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AU - Frank, Franco

AU - Fabrizi, Antonio P.

AU - Frank, Giorgio

AU - Fioravanti, Antonio

PY - 1995

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AB - The authors present a series of 47 patients with craniopharyngiomas treated by stereotaxy in the past 15 years. There was no mortality nor immediate postoperative morbidity in the treatment of the cystic portion of the neoplasm. Intracavitary colloidal yttrium (90Y) was extremely effective in obtaining long-lasting disappearance of craniopharyngioma cysts. In children, yttrium worsened panhypopituitarism, while it was well tolerated by teenagers and adults. Craniopharyngiomas are often mixed (solid-cystic) and the majority of cases have a predominant cystic portion, where stereotaxy is a valid alternative to open surgery, which presents a high morbidity and mortality.

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KW - Intracystic bleomycin

KW - Iodine-125

KW - Yttrium-90

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Stereotactic management of craniopharyngiomas

Abstract

Keywords

ASJC Scopus subject areas

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