TY - JOUR
T1 - Stereotactic radiosurgery for intracranial metastases
T2 - Linac-based and gamma-dedicated unit approach
AU - Alongi, Filippo
AU - Fiorentino, Alba
AU - Mancosu, Pietro
AU - Navarria, Pierina
AU - Giaj Levra, Niccolò
AU - Mazzola, Rosario
AU - Scorsetti, Marta
PY - 2016/7/2
Y1 - 2016/7/2
N2 - ABSTRACT: Introduction: For intracranial metastases, the role of stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy is well recognized. Areas covered: Historically, the first technology, for stereotactic device able to irradiate a brain tumor volume, was Gamma Knife® (GK). Due to the technological advancement of linear accelerator (Linac), there was a continuous increasing interest in SRS Linac-based applications. In those decades, it was assumed a superiority of GK compared to SRS Linac-based for brain tumor in terms of dose conformity and rapid fall-off dose close to the target. Expert commentary: Recently, due to the Linac technologic advancement, the choice of SRS GK-based is not necessarily so exclusive. The current review discussed in details the technical and clinical aspects comparing the two approaches for brain metastases.
AB - ABSTRACT: Introduction: For intracranial metastases, the role of stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy is well recognized. Areas covered: Historically, the first technology, for stereotactic device able to irradiate a brain tumor volume, was Gamma Knife® (GK). Due to the technological advancement of linear accelerator (Linac), there was a continuous increasing interest in SRS Linac-based applications. In those decades, it was assumed a superiority of GK compared to SRS Linac-based for brain tumor in terms of dose conformity and rapid fall-off dose close to the target. Expert commentary: Recently, due to the Linac technologic advancement, the choice of SRS GK-based is not necessarily so exclusive. The current review discussed in details the technical and clinical aspects comparing the two approaches for brain metastases.
KW - Brain metastases
KW - Gamma knife
KW - Linac
KW - Radiotherapy approach
KW - Stereotactic radiosurgery
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U2 - 10.1080/14737140.2016.1190648
DO - 10.1080/14737140.2016.1190648
M3 - Review article
AN - SCOPUS:84976549459
VL - 16
SP - 731
EP - 740
JO - Expert Review of Molecular Diagnostics
JF - Expert Review of Molecular Diagnostics
SN - 1473-7159
IS - 7
ER -