Recently the presence of steroid hormone receptors (SHR) have been reported in a series of human nervous system tumors, mainly in meningiomas. The possibility of characterizing brain tumors deserves attention because of the poor knowledge of the endocrine-related behaviour of such tumors. The reliability of biochemical characterization of various receptor types should allow a better understanding of biological profile of primary and metastatic brain tumors, together with new avenues for combined modality treatment. In the future the highest priority might be assigned to the definition of the cut-off value of positivity for single receptors and to the receptor-endocrine modulation complex relationship for individual patients. A clear definition of the role of SHR in human brain tumors might improve our therapeutic potentials.
|Translated title of the contribution||Steroid receptors in brain tumors|
|Number of pages||6|
|Publication status||Published - 1984|
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