Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease

Domenico Santoro, Irene Colombo, Isabella Ghione, Lorenzo Peverelli, Nereo Bresolin, Monica Sciacco, Alessandro Prelle

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Hashimoto's encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of antithyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt-Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.

Original languageEnglish
Pages (from-to)719-722
Number of pages4
JournalNeurological Sciences
Volume32
Issue number4
DOIs
Publication statusPublished - Aug 2011

Fingerprint

Creutzfeldt-Jakob Syndrome
Steroids
Hashimoto Disease
Immune System Diseases
Movement Disorders
Coma
Prednisone
Nervous System Diseases
Psychiatry
Seizures
Antibodies
Hashimoto's encephalitis

Keywords

  • Anti-thyroid antibodies
  • Encephalopathy
  • Hashimoto
  • Steroids

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology

Cite this

Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease. / Santoro, Domenico; Colombo, Irene; Ghione, Isabella; Peverelli, Lorenzo; Bresolin, Nereo; Sciacco, Monica; Prelle, Alessandro.

In: Neurological Sciences, Vol. 32, No. 4, 08.2011, p. 719-722.

Research output: Contribution to journalArticle

Santoro, Domenico ; Colombo, Irene ; Ghione, Isabella ; Peverelli, Lorenzo ; Bresolin, Nereo ; Sciacco, Monica ; Prelle, Alessandro. / Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease. In: Neurological Sciences. 2011 ; Vol. 32, No. 4. pp. 719-722.
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