Abstract
Hashimoto's encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of antithyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt-Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.
| Original language | English |
|---|---|
| Pages (from-to) | 719-722 |
| Number of pages | 4 |
| Journal | Neurological Sciences |
| Volume | 32 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 2011 |
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Keywords
- Anti-thyroid antibodies
- Encephalopathy
- Hashimoto
- Steroids
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health
- Dermatology
Cite this
Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease. / Santoro, Domenico; Colombo, Irene; Ghione, Isabella; Peverelli, Lorenzo; Bresolin, Nereo; Sciacco, Monica; Prelle, Alessandro.
In: Neurological Sciences, Vol. 32, No. 4, 08.2011, p. 719-722.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt-Jakob disease
AU - Santoro, Domenico
AU - Colombo, Irene
AU - Ghione, Isabella
AU - Peverelli, Lorenzo
AU - Bresolin, Nereo
AU - Sciacco, Monica
AU - Prelle, Alessandro
PY - 2011/8
Y1 - 2011/8
N2 - Hashimoto's encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of antithyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt-Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.
AB - Hashimoto's encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of antithyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt-Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.
KW - Anti-thyroid antibodies
KW - Encephalopathy
KW - Hashimoto
KW - Steroids
UR - http://www.scopus.com/inward/record.url?scp=80054004348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80054004348&partnerID=8YFLogxK
U2 - 10.1007/s10072-011-0610-8
DO - 10.1007/s10072-011-0610-8
M3 - Article
VL - 32
SP - 719
EP - 722
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 4
ER -