Steroid-responsive multifocal demyelinating neuropathy with central involvement

Rocco Liguori; Romana Rizzi; Roberto Vetrugno; Fabrizio Salvi; Alessandra Lugaresi; Sabina Cevoli; Pasquale Montagna

doi:10.1002/(SICI)1097-4598(199902)22:2<262::AID-MUS16>3.0.CO;2-1

Steroid-responsive multifocal demyelinating neuropathy with central involvement

Rocco Liguori, Romana Rizzi, Roberto Vetrugno, Fabrizio Salvi, Alessandra Lugaresi, Sabina Cevoli, Pasquale Montagna

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Abstract

We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.

Original language	English
Pages (from-to)	262-265
Number of pages	4
Journal	Muscle and Nerve
Volume	22
Issue number	2
DOIs	https://doi.org/10.1002/(SICI)1097-4598(199902)22:2<262::AID-MUS16>3.0.CO;2-1
Publication status	Published - 1999

Keywords

Demyelinating neuropathy
Electrophysiological studies
Motor and sensory conduction blocks
Multifocal
Steroid treatment

ASJC Scopus subject areas

Clinical Neurology
Neuroscience(all)

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10.1002/(SICI)1097-4598(199902)22:2<262::AID-MUS16>3.0.CO;2-1

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title = "Steroid-responsive multifocal demyelinating neuropathy with central involvement",

abstract = "We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.",

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AU - Liguori, Rocco

AU - Rizzi, Romana

AU - Vetrugno, Roberto

AU - Salvi, Fabrizio

AU - Lugaresi, Alessandra

AU - Cevoli, Sabina

AU - Montagna, Pasquale

PY - 1999

Y1 - 1999

N2 - We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.

AB - We describe 2 patients with associated central and peripheral demyelination. Electrophysiological studies revealed a demyelinating polyneuropathy with sensory and motor conduction blocks. Visual evoked potentials were abnormal. Motor evoked potentials showed abnormal central conduction time in 1 patient. Magnetic resonance imaging revealed regions of abnormal high signal in the spinal cord and brain; sural nerve biopsy disclosed a demyelinating neuropathy. Both patients showed clinical and electrophysiological improvement after steroid therapy.

KW - Demyelinating neuropathy

KW - Electrophysiological studies

KW - Motor and sensory conduction blocks

KW - Multifocal

KW - Steroid treatment

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Steroid-responsive multifocal demyelinating neuropathy with central involvement

Abstract

Keywords

ASJC Scopus subject areas

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