Strain-dependent variations in the number of forebrain cholinergic neurons

Alberto Albanese, Stefano Gozzo, Carmela Iacopino, Maria Concetta Altavista

Research output: Contribution to journalArticle

Abstract

The morphological organization of putatively cholinergic neurons was studied in the forebrain of two inbred mouse strains (C57BL/6 and DBA/2) by means of acetylcholinesterase pharmacohistochemistry. In both strains, putatively cholinergic perikarya were seen in the caudato-putamen, medial septum, diagonal band, and basal nucleus of Meynert: in all these regions, their distribution was similar in both strains, but their density was significantly higher (from 20 to 32%) in DBA/2 mice. The present data demonstrate the existence of genetically determined differences in the organization of forebrain cholinergic systems.

Original languageEnglish
Pages (from-to)380-384
Number of pages5
JournalBrain Research
Volume334
Issue number2
DOIs
Publication statusPublished - May 20 1985

Keywords

  • acetylcholinesterase
  • basal ganglia
  • basal nucleus of Meynert
  • cholinergic systems
  • forebrain
  • genetic study
  • morphology
  • septal nuclei

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Strain-dependent variations in the number of forebrain cholinergic neurons'. Together they form a unique fingerprint.

  • Cite this