Strenuous exercise activates growth factors and chemokines over-expression in human serum of top-level triathlon athletes during a competitive season.

Giuseppe Banfi, Sergio Migliorini, Francesca Pedroni, Emanuela Galliera, Giada Dogliotti, Alexis E. Malavazos, Massimiliano M. Corsi

Research output: Contribution to journalArticlepeer-review

Abstract

Regular exercise offers protection against all-cause mortality, primarily by protection against atherosclerosis and insulin resistance. There is evidence that physical training is effective as a treatment in patients with chronic heart diseases and type 2 diabetes. With excessive repetition of the training stimulus, local inflammation can generate a systemic inflammatory response. Cytokines play an important role in these processes. Our data confirm that cytokines that are considered to induce systemic bioactivity following exercise are not alone, but also growth factors and chemokines, which are secreted in exercise without the involvement of traditional proinflammatory cytokines, could be potent angiogenic factors.

Original languageEnglish
Pages (from-to)250-252
Number of pages3
JournalClinical Chemistry and Laboratory Medicine
Volume46
Issue number2
DOIs
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Clinical Biochemistry

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