TY - JOUR
T1 - Strenuous exercise activates growth factors and chemokines over-expression in human serum of top-level triathlon athletes during a competitive season.
AU - Banfi, Giuseppe
AU - Migliorini, Sergio
AU - Pedroni, Francesca
AU - Galliera, Emanuela
AU - Dogliotti, Giada
AU - Malavazos, Alexis E.
AU - Corsi, Massimiliano M.
PY - 2008
Y1 - 2008
N2 - Regular exercise offers protection against all-cause mortality, primarily by protection against atherosclerosis and insulin resistance. There is evidence that physical training is effective as a treatment in patients with chronic heart diseases and type 2 diabetes. With excessive repetition of the training stimulus, local inflammation can generate a systemic inflammatory response. Cytokines play an important role in these processes. Our data confirm that cytokines that are considered to induce systemic bioactivity following exercise are not alone, but also growth factors and chemokines, which are secreted in exercise without the involvement of traditional proinflammatory cytokines, could be potent angiogenic factors.
AB - Regular exercise offers protection against all-cause mortality, primarily by protection against atherosclerosis and insulin resistance. There is evidence that physical training is effective as a treatment in patients with chronic heart diseases and type 2 diabetes. With excessive repetition of the training stimulus, local inflammation can generate a systemic inflammatory response. Cytokines play an important role in these processes. Our data confirm that cytokines that are considered to induce systemic bioactivity following exercise are not alone, but also growth factors and chemokines, which are secreted in exercise without the involvement of traditional proinflammatory cytokines, could be potent angiogenic factors.
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U2 - 10.1515/CCLM.2008.050
DO - 10.1515/CCLM.2008.050
M3 - Article
C2 - 18324908
AN - SCOPUS:43349091728
VL - 46
SP - 250
EP - 252
JO - Clinical Chemistry and Laboratory Medicine
JF - Clinical Chemistry and Laboratory Medicine
SN - 1434-6621
IS - 2
ER -