Strenuous resistance to natural HIV-1 disease progression: Viral controllers and long-term nonprogressors

Agostino Riva; Elisa Vicenzi; Massimo Galli; Guido Poli

doi:10.2217/fvl.11.25

Strenuous resistance to natural HIV-1 disease progression: Viral controllers and long-term nonprogressors

Agostino Riva, Elisa Vicenzi, Massimo Galli, Guido Poli

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

HIV-1 infection leads to AIDS and death within 8-10 years for most individuals in the absence of antiretroviral therapy (ART). However, a minority of infected individuals show the unusual capacity to spontaneously control disease progression after infection in the absence of any ART. So-called 'long-term nonprogressors' are defined by maintenance of peripheral CD4 ⁺ T-cell counts >500 cells/μl and good health without ART for >7 years since infection. More recently, ART-naive individuals who spontaneously control their viremia levels at either

Original language	English
Pages (from-to)	521-533
Number of pages	13
Journal	Future Virology
Volume	6
Issue number	4
DOIs	https://doi.org/10.2217/fvl.11.25
Publication status	Published - Apr 2011

Keywords

AIDS
ART
elite controllers
genome-wide association study
HIV
HIV controllers
HLA
long-term nonprogressors
viremia

ASJC Scopus subject areas

Virology

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Strenuous resistance to natural HIV-1 disease progression: Viral controllers and long-term nonprogressors

Abstract

Keywords

ASJC Scopus subject areas

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