Stress echocardiography for risk stratification of patients with chest pain and normal or slightly narrowed coronary arteries

Riccardo Bigi, Lauro Cortigiani, Jeroen J. Bax, Paola Colombo, Alessandro Desideri, Carlo Sponzilli, Cesare Fiorentini

Research output: Contribution to journalArticle

Abstract

One hundred twenty-five patients (60 ± 10 years old, 60 women) with known (35, previous myocardial infarction) or suspected (90) coronary artery disease (CAD) and no more than 50% coronary stenoses underwent pharmacologic (48 dipyridamole and 77 dobutamine) stress echocardiography (SE) and prospective follow-up (36 ± 22 months) for cardiac death, nonfatal infarction, and unstable angina. The ability of clinical and SE variables to predict the outcome was assessed by the Cox model. A significant increase in the global chi-square of the model indicated an incremental prognostic value. Nine events occurred: 2 fatal and 5 nonfatal infarctions and 2 hospitalizations for unstable angina. Hypertension, positive SE, and peak wall motion score index were multivariate predictors of outcome, but SE provided an 87.5% increase in the global chisquare (P <.001). Patients with positive SE had a significantly lower event-free survival compared with those with negative SE. Therefore, we conclude that SE provides incremental prognostic information in patients with chest pain without critical coronary artery disease.

Original languageEnglish
Pages (from-to)1285-1289
Number of pages5
JournalJournal of the American Society of Echocardiography
Volume15
Issue number10 II
DOIs
Publication statusPublished - Oct 1 2002

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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