Stroke in two young siblings with congenital dysfibrinogenemia

A. Quattrone, M. Colucci, M. B. Donati, M. Meduri, L. Mussoni, M. C. Roncaglioni, N. Semeraro, S. Carlomagno, V. Bonavita

Research output: Contribution to journalArticlepeer-review

Abstract

Two young siblings (a male of 21 and his sister of 26 years) suffered from arterial thrombosis episodes of the carotid and abdominal aorta documented by angiographic studies. In the absence of any known predisposing factor in the family and personal history, the laboratory investigation of both patients revealed coagulation abnormalities compatible with a dysfibrinogenemia. The occurrence of a similar defect also in plasma of one of the propositi's asymptomatic relatives is suggestive of an inherited fibrinogen disorder

Original languageEnglish
Pages (from-to)229-232
Number of pages4
JournalItalian Journal of Neurological Sciences
Volume4
Issue number2
DOIs
Publication statusPublished - Jun 1983

Keywords

  • dysfibrinogenemia
  • Stroke
  • thrombin time

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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