Strontium absorption and excretion in normocalciuric subjects: Relation to calcium metabolism

Giuseppe Vezzoli, Ivano Baragetti, Simona Zerbi, Andrea Caumo, Laura Soldati, Piera Bellinzoni, Antonella Centemero, Alessandro Rubinacci, GianLuigi Moro, Giuseppe Bianchi

Research output: Contribution to journalArticle

Abstract

The relationships of Sr intestinal absorption and renal excretion with biohumoral factors regulating Ca metabolism were studied in 47 normocalciuric subjects with Ca kidney stones. Sr concentrations were measured in serum and urine after an oral load of stable Sr (30.2 μmol/kg body wt). Enteral absorption of the ion (9.77 ± 0.438 mmol · L-1 · min, 240 min after Sr administration), expressed as the area under the plasma concentration-time curve (AUC), and renal clearance (CR(E)) in these subjects during the test (2.80 ± 0.336 mL/min) were not different from values for 27 controls. CR(E) was not correlated with AUCs. Plasma concentrations of parathyroid hormone (PTH) negatively correlated with AUCs (P

Original languageEnglish
Pages (from-to)586-590
Number of pages5
JournalClinical Chemistry
Volume44
Issue number3
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Clinical Biochemistry

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    Vezzoli, G., Baragetti, I., Zerbi, S., Caumo, A., Soldati, L., Bellinzoni, P., Centemero, A., Rubinacci, A., Moro, G., & Bianchi, G. (1998). Strontium absorption and excretion in normocalciuric subjects: Relation to calcium metabolism. Clinical Chemistry, 44(3), 586-590.