Structural and ultrastructural defects in preovulatory endometrium of normo-ovulating infertile women with minimal or mild endometriosis

L. Fedele, M. Marchini, S. Bianchi, M. Dorta, L. Arcaini, P. E. Fontana

Research output: Contribution to journalArticle

Abstract

To investigate whether a primary endometrial factor is involved in the pathogenesis of infertility in patients with minimal or mild endometriosis, we compared light, scanning, and transmission electron microscopic studies of preovulatory endometria of 15 endometriotic patients with 12 normal controls. All the women were infertile and normo-ovulating by standard criteria. Six morphometric indexes were considered. The scanning electron microscopic analysis revealed heterogeneity of the endometrial surface epithelium in 77% of the patients with endometriosis and in 16% of the controls. Glandular and stromal mitoses, basal vacuolated cells, and the ciliated:nonciliated cell ratio were significantly reduced in the endometriosis group compared with the controls. Further studies are needed to clarify the role of the observed endometrial anomalies in the pathogenesis of infertility associated with endometriosis.

Original languageEnglish
Pages (from-to)989-993
Number of pages5
JournalFertility and Sterility
Volume53
Issue number6
Publication statusPublished - 1990

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Endometriosis
Endometrium
Infertility
Electrons
Mitosis
Epithelium
Light

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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Structural and ultrastructural defects in preovulatory endometrium of normo-ovulating infertile women with minimal or mild endometriosis. / Fedele, L.; Marchini, M.; Bianchi, S.; Dorta, M.; Arcaini, L.; Fontana, P. E.

In: Fertility and Sterility, Vol. 53, No. 6, 1990, p. 989-993.

Research output: Contribution to journalArticle

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AU - Fontana, P. E.

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