Structural Brain Imaging in Bipolar Disorder

Paolo Brambilla, Jair C. Soares

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationBipolar Disorder: Clinical and Neurobiological Foundations
PublisherJohn Wiley and Sons
Number of pages9
ISBN (Print)9780470721988
Publication statusPublished - Aug 13 2010


  • Basal ganglia, including caudate, putamen and globus pallidus
  • Brain imaging studies, specifically with magnetic resonance imaging (MRI)
  • Declarative memory, conscious recollection, verbal reflection and expression of facts and events - supported by hippocampus
  • Dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC)
  • Structural abnormalities, in bipolar disorder - in anterior cingulate, hippocampus, amygdala and corpus callosum
  • Structural brain imaging in bipolar disorder
  • Subgenual prefrontal cortex (SGPFC)
  • Thalamus, relay station between cortical and subcortical brain regions - crucial for motor and cognitive coordination
  • Val-66-met single nucleotide polymorphism (SNP) - in brain-derived neurotrophic factor (BDNF) gene

ASJC Scopus subject areas

  • Medicine(all)

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