EVOLUZIONE STRUTTURALE DEL DISCO INTERVERTEBRALE DOPO NUCLEOLISI ENZIMATICA E NUCLEOTOMIA PERCUTANEA

Translated title of the contribution: Structural evolution of the intervertebral disk after enzymatic nucleolysis and percutaneous nucleotomy

P. Zerbinati, M. Cannas

Research output: Contribution to journalArticle

Abstract

The aim of this research has been to study histochemical and morphological modifications in the intervertebral disk subjected to two different techniques employed for lumbar disk hernia treatment: chimonucleolysis acting by means of enzymatic nucleolysis and percutaneous nucleotomy acting through mechanical mincing. For this purpose we did a comparative analysis of the discal substance removed during discectomy surgery in ten patients, aged between 19 and 49; five were treated with enzymatic nucleolysis and five with percutaneous nucleotomy and subsequently operated for the symptomatic reappearance after a variable interval of time and we compared it with patients treated in the first place with discectomy surgery. The results have demonstrated how, immediately after the execution of either methods, the nucleus pulpous showed structural modifications, respectively morphological after percutaneuos nucleotomy and histological after chimonucleolysis. These alterations tend to vanish after a longer period of time and reveal how, after a year from execution of one of the two treatments, the nucleus pulpous has regained its original structure through a synthesis of its normal structural components. Even if the patients considered are included in that 30% of failures carried forward in the various case histories, both chemonucleolysis and percutaneuos nucleotomy have shown the efficacy of their immediate action and the lack of destructive effects on the intimate structure of the nucleus pulpous.

Original languageItalian
Pages (from-to)265-270
Number of pages6
JournalMinerva Ortopedica e Traumatologica
Volume45
Issue number7-8
Publication statusPublished - 1994

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Percutaneous Diskectomy
Intervertebral Disc
Diskectomy
Intervertebral Disc Chemolysis
Hernia
Therapeutics
Research

ASJC Scopus subject areas

  • Surgery

Cite this

EVOLUZIONE STRUTTURALE DEL DISCO INTERVERTEBRALE DOPO NUCLEOLISI ENZIMATICA E NUCLEOTOMIA PERCUTANEA. / Zerbinati, P.; Cannas, M.

In: Minerva Ortopedica e Traumatologica, Vol. 45, No. 7-8, 1994, p. 265-270.

Research output: Contribution to journalArticle

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