Structural modifications in membrane glycoproteins during the erythrocyte life-span

Cesare Balduini, Augusta Brovelli, Carlo Luigi Balduini, Edoardo Ascari

Research output: Contribution to journalArticle

Abstract

Erythrocyte membrane glycoproteins undergo various types of modification during the life of the cell in the circulation; when only sialic acid is removed, the younger red cells can be repaired in the liver and return to the circulation. Otherwise, when an autolytic mechanism removing a sialopeptide becomes active as a consequence of the metubolic impairment of the cell, the erythrocyte is probably trapped by the hemocatheretic organs and destroyed.

Original languageEnglish
Pages (from-to)13-22
Number of pages10
JournalLa Ricerca in Clinica e in Laboratorio
Volume9
Issue number1
DOIs
Publication statusPublished - Jan 1979

Keywords

  • Erythrocyte aging and maturation
  • Erythrocyte membrane glycoproteins
  • Membrane sialic acid

ASJC Scopus subject areas

  • Clinical Biochemistry

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