Structural Organization of Dream Experience During Daytime Soremp Sleep of Patients with Narcolepsy Type 1

Carlo Cipolli, Fabio Pizza, Claudia Bellucci, Michela Mazzetti, Giovanni Tuozzi, Stefano Vandi, Giuseppe Plazzi

Research output: Contribution to journalArticlepeer-review

Abstract

STUDY OBJECTIVE: To assess the frequency of dream experience (DE) developed during naps at Multiple Sleep Latency Test (MSLT) by patients with narcolepsy type-1 (NT1) and establish, using story-grammar analysis, the structural organization of DEs developed during naps with sleep onset REM period (SOREMP) sleep compared with their DEs during early-and late-night REM sleep.

METHODS: Thirty drug-free cognitively intact adult NT1 patients were asked to report DE developed during each MSLT nap. Ten NT1 patients also spent voluntarily a supplementary night being awakened during the first-cycle and third-cycle REM sleep. Patients provided dream reports, white dreams and no dreams, whose frequencies were matched in naps with SOREMP vs non-REM (NREM) sleep. All dream reports were then analysed using story-grammar rules.

RESULTS: DE was recalled in detail (dream report) by NT1 patients after 75% of naps with SOREMP sleep and after 25% of naps with NREM sleep. Dream reports were provided by 8 out of 10 NT1 patients after both awakenings from night-time REM sleep. Story-grammar analysis of dream reports showed that SOREMP-DEs are organized as hierarchically ordered sequences of events (so-called dream-stories), which are longer and more complex in the first and fourth SOREMP-naps and are comparable with night-time REM-DEs.

CONCLUSIONS: The similar structural organization of SOREMP-DEs with night-time REM-DEs indicates that their underlying cognitive processes are highly, albeit not uniformly, effective during daytime SOREMP sleep. Given the peculiar neurophysiology of SOREMP sleep, investigating SOREMP-DEs may cast further light on the relationships between the neurophysiological and psychological processes involved in REM-dreaming.

Original languageEnglish
JournalSleep
DOIs
Publication statusE-pub ahead of print - Feb 14 2020

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