Studies of ineffective erythropoiesis and peripheral haemolysis in congenital dyserythropoietic anaemia type II

G. Barosi, M. Cazzola, M. Stefanelli, E. Ascari

Research output: Contribution to journalArticlepeer-review

Abstract

Erythrokinetic parameters were estimated in six patients suffering from congenital dyserythropoietic anaemia type II (CDA II) by means of a mathematical model of iron kinetics. A wide variation in effectiveness of erythroid activity was observed, and a significant negative correlation was found between ineffective erythropoiesis and peripheral haemolysis. In four patients with prominent peripheral haemolysis, splenectomy was carried out. Marked improvement in their clinical condition and in haemoglobin level resulted.

Original languageEnglish
Pages (from-to)243-250
Number of pages8
JournalBritish Journal of Haematology
Volume43
Issue number2
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Hematology

Fingerprint Dive into the research topics of 'Studies of ineffective erythropoiesis and peripheral haemolysis in congenital dyserythropoietic anaemia type II'. Together they form a unique fingerprint.

Cite this