Studies on the sensitivity of anticancer agents of normal human cells in culture.

L. Morasca, G. Balconi, E. Erba, E. Cvitkovic

Research output: Contribution to journalArticle

Abstract

Two biopsies of human periosteal tissue have been tested for sensitivity to several antitumoral agents. The tests were performed during the lifespan of the cultured cells in order to reveal possible variations in sensitivity. The results indicate that the age of the donor affects drug sensitivity; cells obtained from the young donor show a higher growth potential, together with a variable sensitivity and morphology during their life in vitro, while cells from the adult donor have a lower growth potential, a constant sensitivity to chemotherapy and a constant morphology.

Original languageEnglish
Pages (from-to)511-519
Number of pages9
JournalAdvances in Experimental Medicine and Biology
Volume53
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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