Abstract
Two biopsies of human periosteal tissue have been tested for sensitivity to several antitumoral agents. The tests were performed during the lifespan of the cultured cells in order to reveal possible variations in sensitivity. The results indicate that the age of the donor affects drug sensitivity; cells obtained from the young donor show a higher growth potential, together with a variable sensitivity and morphology during their life in vitro, while cells from the adult donor have a lower growth potential, a constant sensitivity to chemotherapy and a constant morphology.
| Original language | English |
|---|---|
| Pages (from-to) | 511-519 |
| Number of pages | 9 |
| Journal | Advances in Experimental Medicine and Biology |
| Volume | 53 |
| Publication status | Published - 1975 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Studies on the sensitivity of anticancer agents of normal human cells in culture. / Morasca, L.; Balconi, G.; Erba, E.; Cvitkovic, E.
In: Advances in Experimental Medicine and Biology, Vol. 53, 1975, p. 511-519.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Studies on the sensitivity of anticancer agents of normal human cells in culture.
AU - Morasca, L.
AU - Balconi, G.
AU - Erba, E.
AU - Cvitkovic, E.
PY - 1975
Y1 - 1975
N2 - Two biopsies of human periosteal tissue have been tested for sensitivity to several antitumoral agents. The tests were performed during the lifespan of the cultured cells in order to reveal possible variations in sensitivity. The results indicate that the age of the donor affects drug sensitivity; cells obtained from the young donor show a higher growth potential, together with a variable sensitivity and morphology during their life in vitro, while cells from the adult donor have a lower growth potential, a constant sensitivity to chemotherapy and a constant morphology.
AB - Two biopsies of human periosteal tissue have been tested for sensitivity to several antitumoral agents. The tests were performed during the lifespan of the cultured cells in order to reveal possible variations in sensitivity. The results indicate that the age of the donor affects drug sensitivity; cells obtained from the young donor show a higher growth potential, together with a variable sensitivity and morphology during their life in vitro, while cells from the adult donor have a lower growth potential, a constant sensitivity to chemotherapy and a constant morphology.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016414603&partnerID=8YFLogxK
M3 - Article
VL - 53
SP - 511
EP - 519
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
SN - 0065-2598
ER -