Study of autoantibodies and the relationship between anticardiolipin antibodies and lupus anticoagulant in female patients with pregnancy-induced arterial hypertension

F. Cerneca, A. Bacci, R. Abrami, R. Simeone, C. Volpe, F. Scrimin, M. Mangiarotti

Research output: Contribution to journalArticle

Abstract

The aim of this study was to evaluate the relationship between anticardiolipin antibodies and lupus anticoagulant, and the prevalence of autoantibodies in a group of 48 hypertensive third trimester pregnant women. There was no correlation between levels of anticardiolipin and tests of lupus anticoagulant activity. Prevalence of autoantibodies was low, and the presence of anticardiolipin antibodies was not a marker for severe hypertension, trisymptomatic gestosis, or intrauterine growth retardation. In conclusion, our study did not reveal the presence of antiphospholipid antibodies in hypertensive third trimester pregnant women, but the results failed to show any concordance between anticardiolipin antibodies and lupus anticoagulant activity.

Original languageEnglish
Pages (from-to)223-227
Number of pages5
JournalTrasfusione del Sangue
Volume43
Issue number4
Publication statusPublished - 1998

Keywords

  • Anticardiolipin antibodies
  • Hypertension in pregnancy
  • Lupus anticoagulant

ASJC Scopus subject areas

  • Hematology
  • Immunology and Allergy

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