Study of hypoglycemic patients by the glucose clamp technique using the artificial pancreas

A. E. Pontiroli, A. Secchi, M. Dabandi, M. Alberetto, E. Bosi, S. Fantaguzzi, G. Pozza

Research output: Contribution to journalArticlepeer-review

Abstract

Using the artificial pancreas, blood glucose levels were maintained at 80 mg/dl in 9 hypoglycemic patients (4 with histologically proven insulinomas and 5 with nontumoral hypoglycemia) and in 4 normal subjects during a 24-h fast. The amount of glucose used, serum insulin levels, and glucose clearance were higher in patients with nontumoral hypoglycemia than in normal subjects and highest in the patients with an insulinoma. Surgical or pharmacological treatment resulted in normalization of all parameters. In contrast to the 72-h fast, the 24-h glucose clamp technique allowed the study of hypoglycemic patients without inducing hazardous hypoglycemia.

Original languageEnglish
Pages (from-to)1297-1300
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Volume57
Issue number6
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology, Diabetes and Metabolism

Fingerprint Dive into the research topics of 'Study of hypoglycemic patients by the glucose clamp technique using the artificial pancreas'. Together they form a unique fingerprint.

Cite this