Study of neurological and neurophysiological impairment in carbon disulphide workers

R. Gilioli, C. Bulgheroni, P. A. Bertazzi, A. M. Cirla, M. Tomasini, M. G. Cassitto, M. T. Jacovone

Research output: Contribution to journalArticlepeer-review


A neurological, electromyographic, electroneurographic, electroencephalographic and ophthalmoscopic investigation was performed on a large group of viscose production workers with different exposure to carbon disulphide and on 54 non-exposed workers as referents. The psycho-organic disturbances and the minimal neuropathy represent the prominent response of the nervous system to the action of carbon disulphide, which has been found after five years of exposure of up to 60 mg/m 3. Clear-cut encephalopathies and polyneuropathies are found infrequently in a population at work. Ophthalmoscopic vascular findings are frequent and show some relation with exposure. EMG results and conduction velocity reduction are correlated with exposure and can furnish significant data already within the first four years of exposure. The statistical increase of increase of residual latency suggests an initial distal site of action of carbon disulphide at the level of the distal nerve intramuscular branches. Statistical analysis confirms the influence of alcohol intake in producing, as a co-factor, the central and peripheral pictures found in this study.

Original languageEnglish
Pages (from-to)130-143
Number of pages14
JournalMedicina del Lavoro
Issue number2
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


Dive into the research topics of 'Study of neurological and neurophysiological impairment in carbon disulphide workers'. Together they form a unique fingerprint.

Cite this