STUDIO DI NOVE PROTEINE SERICHE IN CORSE DI EPATITE PERSISTENTE, EPATITE CRONICA AGGRESSIVA E CIRROSI POSTEPATITICA

Translated title of the contribution: Study of nine serum proteins in persistent hepatitis, aggressive chronic hepatitis and posthepatitis cirrhosis

A. Agostoni, B. Marasini, M. Pontello

Research output: Contribution to journalArticlepeer-review

Abstract

Prealbumin, albumin, orosomucoid α(1) antitrypsin, α(2) macroglobulin, β(1c)/β(1A) globulin, IgG, IgA and IgM were quantitatively determined in the serum of patients with persistent hepatitis, chronic aggressive hepatitis and postnecrotic cirrhosis. Albumin, orosomucoid, and mainly prealbumin were significantly reduced in all of the three groups. By contrast, α(1) antitrypsin and α(2) macroglobulin were never reduced. β(1c)/β(1A) globulin was increased in the case of persistent hepatitis and reduced in postnecrotic cirrhosis. IgG began to increase during persistent hepatitis, while IgA were significantly increased only in the group of postnecrotic cirrhosis. Finally, IgM were increased in chronic aggressive hepatitis and postnecrotic cirrhosis. A comparison has been done between the data of the group of postnecrotic cirrhosis and the data obtained from a group of alcoholic cirrhosis previously examined: in the latter group the reduction of prealbumin and albumin was less pronounced, while the increase of IgA was more evident.

Translated title of the contributionStudy of nine serum proteins in persistent hepatitis, aggressive chronic hepatitis and posthepatitis cirrhosis
Original languageItalian
Pages (from-to)101-109
Number of pages9
JournalOspedale Maggiore
Volume68
Issue number2
Publication statusPublished - 1973

ASJC Scopus subject areas

  • Medicine(all)

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