Prealbumin, albumin, orosomucoid α(1) antitrypsin, α(2) macroglobulin, β(1c)/β(1A) globulin, IgG, IgA and IgM were quantitatively determined in the serum of patients with persistent hepatitis, chronic aggressive hepatitis and postnecrotic cirrhosis. Albumin, orosomucoid, and mainly prealbumin were significantly reduced in all of the three groups. By contrast, α(1) antitrypsin and α(2) macroglobulin were never reduced. β(1c)/β(1A) globulin was increased in the case of persistent hepatitis and reduced in postnecrotic cirrhosis. IgG began to increase during persistent hepatitis, while IgA were significantly increased only in the group of postnecrotic cirrhosis. Finally, IgM were increased in chronic aggressive hepatitis and postnecrotic cirrhosis. A comparison has been done between the data of the group of postnecrotic cirrhosis and the data obtained from a group of alcoholic cirrhosis previously examined: in the latter group the reduction of prealbumin and albumin was less pronounced, while the increase of IgA was more evident.
|Translated title of the contribution||Study of nine serum proteins in persistent hepatitis, aggressive chronic hepatitis and posthepatitis cirrhosis|
|Number of pages||9|
|Publication status||Published - 1973|
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