Study of serial lymphocyte subsets in multiple sclerosis: their possible role in the evaluation of disease progression.

C. L. Cazzullo, M. Zaffaroni, D. Caputo, A. Ghezzi

Research output: Contribution to journalArticlepeer-review

Abstract

We followed-up 30 patients with definite multiple sclerosis (MS) for one year recording monthly: clinical evolution, neurological examination and T-lymphocyte subsets in peripheral blood recognized by monoclonal antibodies. Although clinical relapses could not be strictly associated with lymphocyte abnormalities in all cases, the parallel clinical-immunological survey permitted to correlate significantly the type of clinical course (chronic-progressive, relapsing, stable) with a correspondent immunological pattern (steadily high, transiently high, steadily normal CD4/CD8 ratios respectively). Our results suggest a possible role of serial lymphocyte subsets analysis in defining evolution of MS.

Original languageEnglish
Pages (from-to)24-26
Number of pages3
JournalRivista di Neurologia
Volume57
Issue number1
Publication statusPublished - Jan 1987

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Study of serial lymphocyte subsets in multiple sclerosis: their possible role in the evaluation of disease progression.'. Together they form a unique fingerprint.

Cite this