Study of the HLA-DPβ1 locus by the polymerase chain reaction technique in patients with Hodgkin's disease

G. Pellegris, C. Lombardo, A. Cantoni, L. Devizzi, M. Balzarotti

Research output: Contribution to journalArticlepeer-review

Abstract

Background: A number of reports have studied associations between Hodgkin's disease and HLA. Some of them established correlation between several antigens and Hodgkin's disease, and others found no correlations. Methods: The HLA DP locus was determined by the polymerase chain reaction method in 31 Hodgkin's disease patients and 58 healthy controls. Results: No significant difference between patients and controls was noted. Conclusions: Further investigations are needed to confirm the hypothesis of a possible role of the HLA complex as one of the factors involved in Hodgkin's disease.

Original languageEnglish
Pages (from-to)133-136
Number of pages4
JournalTumori
Volume79
Issue number2
Publication statusPublished - 1993

Keywords

  • HLA
  • Hodgkin's disease
  • polymerase chain reaction

ASJC Scopus subject areas

  • Cancer Research

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