Abstract
Basal and stimulated GH and PRL secretions were studied in 4 patients with myotonic dystrophy. High values of basal plasma GH were occasionally found in 2 patients. Abnormal plasma GH responses coexisted with normal ones after each stimulus (oral l-dopa, oral glucose load, arginine infusion, i.v. insulin, i.v. metoclopramide). Basal plasma PRL levels were normal in all patients as well as responses to different stimuli except the response to insulin-induced hypoglycemia that was abnormal in 3 patients out of 4. It is concluded that in myotonic dystrophy hypothalamic regulatory mechanisms of pituitary functions may be altered because of known thalamic lesions or, as yet, unrecognized hypothalamic ones.
| Original language | English |
|---|---|
| Pages (from-to) | 178-184 |
| Number of pages | 7 |
| Journal | Acta Neurologica Belgica |
| Volume | 82 |
| Issue number | 3 |
| Publication status | Published - 1982 |
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ASJC Scopus subject areas
- Clinical Neurology
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Study on growth hormone and prolactin secretions in myotonic dystrophy. / Canal, N.; Smirne, S.; Comi, G.; Guidobono, F.; Pecile, A.; Caviezel, F.
In: Acta Neurologica Belgica, Vol. 82, No. 3, 1982, p. 178-184.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Study on growth hormone and prolactin secretions in myotonic dystrophy
AU - Canal, N.
AU - Smirne, S.
AU - Comi, G.
AU - Guidobono, F.
AU - Pecile, A.
AU - Caviezel, F.
PY - 1982
Y1 - 1982
N2 - Basal and stimulated GH and PRL secretions were studied in 4 patients with myotonic dystrophy. High values of basal plasma GH were occasionally found in 2 patients. Abnormal plasma GH responses coexisted with normal ones after each stimulus (oral l-dopa, oral glucose load, arginine infusion, i.v. insulin, i.v. metoclopramide). Basal plasma PRL levels were normal in all patients as well as responses to different stimuli except the response to insulin-induced hypoglycemia that was abnormal in 3 patients out of 4. It is concluded that in myotonic dystrophy hypothalamic regulatory mechanisms of pituitary functions may be altered because of known thalamic lesions or, as yet, unrecognized hypothalamic ones.
AB - Basal and stimulated GH and PRL secretions were studied in 4 patients with myotonic dystrophy. High values of basal plasma GH were occasionally found in 2 patients. Abnormal plasma GH responses coexisted with normal ones after each stimulus (oral l-dopa, oral glucose load, arginine infusion, i.v. insulin, i.v. metoclopramide). Basal plasma PRL levels were normal in all patients as well as responses to different stimuli except the response to insulin-induced hypoglycemia that was abnormal in 3 patients out of 4. It is concluded that in myotonic dystrophy hypothalamic regulatory mechanisms of pituitary functions may be altered because of known thalamic lesions or, as yet, unrecognized hypothalamic ones.
UR - http://www.scopus.com/inward/record.url?scp=0020266456&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020266456&partnerID=8YFLogxK
M3 - Article
VL - 82
SP - 178
EP - 184
JO - Acta Neurologica Belgica
JF - Acta Neurologica Belgica
SN - 0300-9108
IS - 3
ER -