Subcutaneous octreotide in the treatment of pain in advanced cancer patients

Franco De Conno, Luigi Saita, Carla Ripamonti, Vittorio Ventafridda

Research output: Contribution to journalArticlepeer-review


Octreotide is a synthetic somatostatin analogue that has been recently tested by various routes of administration as an analgesic drug for different types of pain. The authors evaluated the analgesic efficacy of a subcutaneous 200-ng bolus of octreotide on somatic and visceral pain from advanced cancer in a randomized, single-blind crossover study. The results in nine cases did not show an analgesic effect superior to that of a placebo. Pain relief was obtained in one case of postprandial visceral pain. This case is discussed in detail, and another possible clinical use for octreotide in a particular form of neoplastic pain is hypothesized.

Original languageEnglish
Pages (from-to)34-38
Number of pages5
JournalJournal of Pain and Symptom Management
Issue number1
Publication statusPublished - 1994


  • Cancer pain
  • octreotide
  • subcutaneous route

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology
  • Neurology
  • Nursing(all)


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