Subcutaneous panniculitis lymphoma: Erythema nodosum-Like

Massimiliano Risulo, Pietro Rubegni, Paolo Sbano, Simona Sammassimo, Maria Caterina De Nisi, Lorenzo Leoncini, Clelia Miracco, Michele Fimiani

Research output: Contribution to journalArticlepeer-review


We report the case of a patient who presented with painful nodular subcutaneous lesions on the lower limbs and episodes of high temperature (> 39.50°C). Histologic examination and immunohistochemical study of a biopsy specimen from a nodular lesion were consistent with the diagnosis of subcutaneous panniculitis-like T-cell lymphoma, a rare form of non-Hodgkin lymphoma. Diagnosis is made particularly difficult, especially in the early stages, by nonspecific clinical features shared by many types of panniculitis. Therefore, it seems advisable to consider the possibility of this type of lymphoma in all cases of panniculitis and to perform careful and continuous follow-up of all cases in which a clear diagnosis is not formulated at the outset, with regular repetition of skin biopsies at appropriate intervals.

Original languageEnglish
Pages (from-to)239-241
Number of pages3
JournalClinical Lymphoma and Myeloma
Issue number3
Publication statusPublished - Nov 2006


  • Cutaneous T-cell lymphoma
  • Hemophagocytic syndrome
  • Non-Hodgkin lymphoma

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology


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