Abstract
It has been recently shown that frog motoneurons and their nerve terminals contain calcitonin gene-related peptide-like immunoreactivity in large dense-core vesicles (Matteoli et al., Proc. natn. Acad. Sci. U.S.A. 85, 7366-7370, 1988). We report here by an immunofluorescence approach that the same neurons and nerve terminals also contain substance P-like immunoreactivity. The demonstration of substance P-like immunoreactivity in the frog motor nerve endings supports previous data suggesting a physiological role for this peptide in the modulation of cholinergic transmission.
Original language | English |
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Pages (from-to) | 271-275 |
Number of pages | 5 |
Journal | Neuroscience |
Volume | 37 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1990 |
ASJC Scopus subject areas
- Neuroscience(all)