Subthalamic somatosensory evoked potentials in Parkinson's disease

Alessandra Pesenti, Alberto Priori, Marco Locatelli, Marcello Egidi, Paolo Rampini, Filippo Tamma, Elena Caputo, Valentina Chiesa, Sergio Barbieri

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Deep brain stimulation (DBS) of subthalamic nucleus (STN) is an effective treatment for advanced Parkinson's disease. It also provides an opportunity to record neural activity from the human basal ganglia. In this study, to investigate the involvement of the human STN in sensory functions, we recorded somatosensory evoked potentials (SEPs) elicited by contralateral median-nerve stimulation, from STN electrodes implanted for DBS in patients with Parkinson's disease. We suggest that the STN N18 component of SEPs in Parkinson's disease is a mainly local field potential elicited by muscle afferent input to the nucleus.

Original languageEnglish
Pages (from-to)1341-1345
Number of pages5
JournalMovement Disorders
Volume18
Issue number11
DOIs
Publication statusPublished - Nov 2003

Fingerprint

Subthalamic Nucleus
Somatosensory Evoked Potentials
Parkinson Disease
Deep Brain Stimulation
Implanted Electrodes
Median Nerve
Basal Ganglia
Human Activities
Muscles
Therapeutics

Keywords

  • Deep brain stimulation (DBS)
  • Evoked potentials
  • Parkinson's disease
  • Somatosensory processing
  • Subthalamic nucleus (STN)

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Subthalamic somatosensory evoked potentials in Parkinson's disease. / Pesenti, Alessandra; Priori, Alberto; Locatelli, Marco; Egidi, Marcello; Rampini, Paolo; Tamma, Filippo; Caputo, Elena; Chiesa, Valentina; Barbieri, Sergio.

In: Movement Disorders, Vol. 18, No. 11, 11.2003, p. 1341-1345.

Research output: Contribution to journalArticle

Pesenti, A, Priori, A, Locatelli, M, Egidi, M, Rampini, P, Tamma, F, Caputo, E, Chiesa, V & Barbieri, S 2003, 'Subthalamic somatosensory evoked potentials in Parkinson's disease', Movement Disorders, vol. 18, no. 11, pp. 1341-1345. https://doi.org/10.1002/mds.10519
Pesenti, Alessandra ; Priori, Alberto ; Locatelli, Marco ; Egidi, Marcello ; Rampini, Paolo ; Tamma, Filippo ; Caputo, Elena ; Chiesa, Valentina ; Barbieri, Sergio. / Subthalamic somatosensory evoked potentials in Parkinson's disease. In: Movement Disorders. 2003 ; Vol. 18, No. 11. pp. 1341-1345.
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