Abstract
Background: There is still a matter of controversy whether a subtotal gastrectomy has the same therapeutic potential as a total gastrectomy in distal gastric cancer. Whether all or a subgroup of patients can benefit from total gastrectomy can be answered only by a randomized trial. Method: We therefore assembled a prospective randomized multi-institutional trial which has so far randomized 400 patients for total or subtotal gastrectomy and second level lymphadenectomy. Material: Patients with gastric carcinoma of the lower half of the stomach are eligible unless one of the following conditions exists: Age over 75 years, previous malignant neoplasia except skin cancer, previous gastric resection, high surgical risk, tumor located at less than six centimeters from cardia, tumors not radically resectable. Results: The accrual of patients is still in progress. The available results concern the mortality rate that is higher after total gastrectomy but not statistically different from subtotal resection.
Original language | English |
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Pages (from-to) | 84-91 |
Number of pages | 8 |
Journal | Oncology Research and Treatment |
Volume | 15 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1992 |
Keywords
- Gastric cancer
- Nutritional sequelae
- Subtotal gastrectomy
- Total gastrectomy
ASJC Scopus subject areas
- Cancer Research
- Hematology
- Oncology