Successful palliative approach with high-intensity focused ultrasound in a patient with metastatic anaplastic pancreatic carcinoma: A case report

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Abstract

We report a case of a 74-year-old man with a metastatic anaplastic pancreatic carcinoma (APC). After an early tumour progression on first-line chemotherapy with cisplatin and gemcitabine, even though it was badly tolerated, he was treated with a combination of systemic modified FOLFIRI and high-intensity focused ultrasound (HIFU) on the pancreatic mass. A tumour showing partial response with a clinical benefit was obtained. HIFU was preferred to radiotherapy because of its shorter course and minimal side effects, in order to improve the patient's clinical conditions. The patient is currently on chemotherapy, asymptomatic with a good performance status. In referral centres, with specific expertise, HIFU could be safely and successfully combined with systemic chemotherapy for treatment of metastatic pancreatic carcinoma.

Original languageEnglish
Article number635
Journalecancermedicalscience
Volume10
DOIs
Publication statusPublished - Apr 21 2016

Keywords

  • Abscopal effect
  • Anaplastic pancreatic carcinoma
  • HIFU
  • Palliative treatment

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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